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Nitric Oxide

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Inside the human body nitric oxide is a highly reactive gas that participates in many chemical reactions that effect the quality of yoour health. NO(Nitric Oxide) is prodcued in the body by the breaking down by enzymes in the body of the amino acid arginine.

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Both arginine and alpha-ketoglutaric acid are precursors to nitric oxide (NO) production. The rate-limiting step of amino acid uptake into skeletal muscle is the transportation of the amino acids through the blood to the skeletal muscle, which is governed by blood flow. NO vasodilates blood vessels, thereby increasing blood flow. This increase when combined with exercises means greater blood flow and greater amino acid deliver and uptake in the working skeletal muscle. Exercise itself results in an increase in NO production, and the increased blood flow created by exercise is believed to be linked to the increase in protein synthesis post workout.

Arginine is a precursor for NO production. Supplementing with exogenous Arginine increases NO production and therefore blood vessel dilation and blood flow, which will also for great nutrient deliver (i.e. amino acids) to skeletal muscle. Arginine is also involved in hormone secretion, wound healing, and immune system functioning (Tong & Barbul 2004).

Alpha-ketoglutaric acid is a vital intermediate in the Kreb's energy cycle, used in the formation of amino acids, and a nitrogen/ammonia transporter. The combination of alpha-ketoglutaric acid's benefits with arginine's benefits give AAGK a clear edge over standard L-arginine.

Seeing that nitric oxide (NO) is as a major signaling molecule in neurons and in the immune system, either acting within the cell in which it is produced or by penetrating cell membranes to affect adjacent cells. Nitric oxide is generated from arginine by the action of nitric oxide synthase (NOS). NO has a half-life of only a few seconds in vivo. However, since it is soluble in both aqueous(water) and lipid(fat) media, it readily diffuses through the cytoplasm and plasma membranes of your cells.

Benenfit of Nitric Oxide Supplementation:

Conclusion: NO is an important endogenous pulmonary vasodilator. As a vasodilator, nitric oxide has the ability to increase your body’s ability to deliver blood to working muscles. More blood means more oxygen and nutrients that are being pumped into skeletal muscles. All this translates into bigger, fuller pumps and better overall gains. In fact, with NO, you can expect increased muscle size, strength, endurance, and quicker recovery times.

Bodybuilding Supplement Benefits

Daily Usage

Builds Muscle

Post Workout

Improves Recovery

Average Usage: 1-2 Scoops or 2-3 Tablets/Capsules 1-2 times a day for general use, and usually taken 30-45 minutes before training.

Affordability: Ranges form medium to medium-high, always buy pure form of creatine. Look for reputable manufactures and alway seek the most purest forms of ingreidents available in the market today.

Refrences:

  • 1: Raúl Bescós 1 , Antoni Sureda, Josep A Tur, Antoni Pons "The effect of nitric-oxide-related supplements on human performance" - https://pubmed.ncbi.nlm.nih.gov/22260513/
  • 2: "Supplement muscles in on the market". National Review of Medicine. 2004-07-30. Archived from the original on 2006-11-16. Retrieved 2011-05-25.
  • 3: International Society of Sports Nutrition Conference Proceedings. Sports Nutrition Review Journal, 1: S1-11, 2004.
  • 4: Culotta, Elizabeth; Koshland, Daniel E. Jr. (1992). "NO news is good news". Science. 258 (5090): 1862–1864. Bibcode:1992Sci...258.1862C. doi:10.1126/science.1361684. PMID 1361684.

Tags: Athlete Nutrition Supplements Amino Acids Muscle Builder Pre-Workout Male Health Female Health

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